Rabies vaccine preserved by vaporization is thermostable and immunogenic
نویسندگان
چکیده
منابع مشابه
A thermostable messenger RNA based vaccine against rabies
Although effective rabies virus vaccines have been existing for decades, each year, rabies virus infections still cause around 50.000 fatalities worldwide. Most of these cases occur in developing countries, where these vaccines are not available. The reasons for this are the prohibitive high costs of cell culture or egg grown rabies virus vaccines and the lack of a functional cold chain in many...
متن کاملNewcastle disease virus-vectored rabies vaccine is safe, highly immunogenic, and provides long-lasting protection in dogs and cats.
Effective, safe, and affordable rabies vaccines are still being sought. Newcastle disease virus (NDV), an avian paramyxovirus, has shown promise as a vaccine vector for mammals. Here, we generated a recombinant avirulent NDV La Sota strain expressing the rabies virus glycoprotein (RVG) and evaluated its potential to serve as a vaccine against rabies. The recombinant virus, rL-RVG, retained its ...
متن کاملEbola vaccine is safe and immunogenic, results show.
The first results from a trial of a candidate Ebola virus vaccine show that it is safe and immunogenic, says a paper published online in the New England Journal of Medicine. Researchers at the University of Oxford said the results showed that the vaccine, the first batch of which has already been shipped to Liberia, was safe for testing in volunteers in west Africa. Some 60 healthy volunteers w...
متن کاملImmunogenicity of BHK-Rabies Vaccine in Cattle
In this study, the immunogenicity of a rabies vaccine that was used in one of the Isfahan cattle farms is reported. This vaccine was produced by replication of the Pasteur virus (PV) strain on BHK-21 monolayer cell culture. The virus suspension was inactivated by ß-propiolactone treatment and the harvested pool showed sterility and safety. Thus, the obtained vaccine was tested on mice and a sat...
متن کاملImproving Rabies Vaccine Baits
The U.S. Department of Agriculture distributes more than 10 million tetracycline-containing rabies vaccine baits to control the spread of wildlife-vectored rabies to humans, pets, and livestock. To estimate the percent of target species consuming the baits, raccoons were collected in baited areas and teeth were analyzed for the presence of the tetracycline biomarker. Several incidents of low bi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Vaccine
سال: 2015
ISSN: 0264-410X
DOI: 10.1016/j.vaccine.2015.03.025